Ovarian Cancer ~ Ovarian Cancer News

Ovarian Cancer News ; daily Ovarian Cancer updates from hundreds of medical resources. Ovarian Cancer digests, journals, abstracts, breaking news, clinical trials, research, genetics,new drugs, trials, Chemotherapy, " In the News" drugs on the Horizon, daily updates on Ovarian Cancer information & Medical news. Resources. Blog Keeper; Khrissy Lupinacci Diagnosed 3/06/02 at age 38 with stage 3 C Clear Cell Ovarian Cancer. Soulsink@optonline.net 631.334-1979

Your Questions Answered:

What is your goal and mission for this blog? Goal : to foster collaboration across institutional lines and hasten a cure for Ovarian Cancer. Mission: to break down the barriers, financial, professional or institutional that can limit progress, and instead bring together the best ideas and resources from the worlds of medicine, academia, government and business. What do you hope to achieve? Hope !! I hope that this blog serves as a resource to patients and the scientific and medical communities as a vehiche to HOPE for the GREATER GOOD of all people. We MUST continue to move the field forward! The sign on the door of Hope reads " PUSH " . Knock and they might not answer. Why? Because God said so. " Who then can so softly bind up the wound of another as he who has felt the same wound himself. " Thomas Jefferson Khrissy Lupinacci, Survivor/Advocate. Diagnosed 3/06/02 with Stage 3 C Clear Cell Ovarian Cancer at age 38. SoulsINK@optonline.net

Tips from a Survivor

1.) This is your life, You are the Navigator, steer the ship, take control, allow others to tend to the precious vessel while you chart your course & steer straight ahead
2.) Don't give up, navigate with hope as your guide.Gain a sense of control.Be assertive instead of aggressive. "Assert" your feelings, opinions, or beliefs instead of becoming angry, combative, or passive
3.) Ask for help, delegate jobs. often people want to help but just don't know how or what to do. Let them, walk the dog, wash dishes, paint the fence, do laundry, it makes them feel as though they are aiding in your recovery.
4.) Believe in your treatment, Chemotherapy is a medicine.
5.) Keep fresh flowers near your bedside, desk, kitchen or living area..As with sickness, flowers emerge from a once cold and barren setting, they bloom with hope.
6.) Laugh, be silly, do something uncommon-make yourself laugh. Laughter is good for the soul, spirit and well-being. In my opinion if your not laughing or smiling you are not living.
Attitude determines how I handle and survive life. We can become what we believe, I lovingly tend the garden of my mind. Pull out all the negative weeds and make room for positive affirmations to grow.
Breathe!!! Relax, close your eyes. breathe normally through your nose. As you exhale, silently say to yourself the word " Calm " or " Heal" or " Quiet" or "Peace" BREATHE...Inhale, exhale..breathe evenly; do not hold your breath.Do this several times a day for 3-5 minutes---when feeling anxious or stressed or simply need to refresh your mind or spirit. IT WORKS!!!
Create a sacred Space; find a space or small spot that refreshes your spirit and calms your mind. Create a healing ambiance, small fountain, wind chimes, music, soft fabrics, pillows, buy a CD with nature sounds, raindrops, birds, the oceans roar, create a calming presence. Center your spirit amidst the healing ambiance. Drink some warm tea, close your eyes and breathe.
Discover a new talent, try your hand in painting, clay, beading, sewing, needlepoint, crocheting, ceramics, knitting, photography, weaving, looming. Busy yourself, uncover your Picasso or Monet. Keep your hands and mind busy, an idle mind is truly the devils workshop. Too much time to think conjurs up dark and dreary thoughts. Busy yourself with hopefulness rather than dreadfulness.
Do something you've always wanted to do but could not find the time to do, just do it. Be Brave, be Bold, behold life.
During Chemo & healing- Sleep when you need to sleep, nap when you need to nap, sleep is essential to healing.
During Chemo, pamper yourself, get a manicure, pedicure, facial, massage, buy new earrings, a new lipstick, or new blouse.
During Chemo- take along your favorite blanket, fuzzy socks, slippers or pillow- make yourself comfortable during these uncomfortable times.
Eliminate STRESS, stressors & toxic beings. Of course it's difficult to eliminate all stress- but it is possible to remove the undesirables and replace them with desirables.
Find Support. Support groups are a very useful sharing experience. They provide an environment in which you can learn new ways of dealing with your illness.You will gain strength in knowing that you are not facing hardships alone.Remember that others may share information or experiences that do not apply to you. Never replace your doctor's advice with that of another patient.
Keep a positive attitude..Believe in your doctors- together you form a team.
Plant a garden, small herb garden, vegetable garden, rose garden, perennial garden, keep your hands & mind busy--nurture your garden & nurture your soul.
Play music, dance, tap your feet, let your soul dance.
Put something on your calendar every week or every month to look forward to.
Tea, hot tea, cold tea, iced tea, green tea, black tea----Have a Tea Party!!
Treatment Day, plan to go shopping afterwards, or a nice lunch or dinner or visit with friends. Fill the day with something enjoyable.

Great Ovarian Cancer Discussion List- Acor.org

Ovarian Cancer Risk Factors:

Age (over 50 years). Highest occurrence in women over 50. However' all females are at risk at all ages and stages of life.
Family / personal history of ovarian, breast, endometrial, or colon cancer
History of ovarian cancer in your immediate family.
Hormone replacement therapy in post-menopausal women very slightly increases the risk for ovarian cancer.
Infertility drug use- a nearly 3-fold increase in risk was found, with a substantially greater risk in those who fail to conceive. However, this is not a consistent finding and most of these "carcinomas" are borderline tumors.
No children (the greater the number of pregnancies, the lower the risk for developing ovarian cancer)
Presence of BRCA1 Or BRCA2 gene mutations.
Race-ovarian cancer occurs 50% more frequently in white women than African American women.
Uninterrupted ovulation, i.e., no pregnancies or infertility

National Cancer Institute Estimation of news cases of Ovarian Cancer 2007

Ovarian Cancer Symptons

Ovarian cancer is difficult to diagnose because symptoms often do not occur until late in the disease. Symptoms do not occur until the tumor has grown large enough to apply pressure to other organs in the abdomen, or until the cancer has spread to remote organs. The symptoms are nonspecific, meaning they could be due to many different conditions. Cancer is not usually the first thing considered in a woman having symptoms. The only early symptom of the disease is menstrual irregularity. Ovarian Cancer Symptoms • Pelvic pain or pressure • Pain with intercourse • Abdominal swelling and bloating • Urinary frequency • Constipation • Ascites - Collection of fluid in the abdomen, contributing to abdominal distension and shortness of breath • Loss of appetite • Feeling full after even small amounts • Gas and/or diarrhea • Nausea and vomiting • Abnormalities in menstruation, pubertal development, and abnormal hair growth (with tumors that secrete hormones) • Back pain (Sciatica)

Risks

Some of the risk factors for the most common (epithelial) type of ovarian cancer are: Age: Most ovarian cancers happen after menopause. Half of all these cancers are found in women over the age of 65 . * Though All Females are at Risk-Ovarian Cancer can strike at ANY AGE. Women who have never had children are more likely to develop ovarian cancer than those who have had children. Pregnancy, tubal ligation and the use of oral contraceptives appear to reduce the risk of developing ovarian cancer. Fertility drugs and hormone replacement therapy: Long term use of these drugs increases the risk. Family history: Ovarian cancer risk is higher among women whose close blood relatives (mother, sister, daughter) have (or had) this disease. The relatives can be from either the mother's or father's side of the family. There is a higher risk if family members were diagnosed with ovarian cancer at an early age. Breast cancer: Women who have had breast cancer also have a higher risk of ovarian cancer. Recent studies suggested that preventive surgery to remove the ovaries and fallopian tubes can decrease the risk of ovarian cancers and other gynecologic cancers in women with BRCA1 and BRCA2 mutations. Another genetic syndrome, hereditary non-polyposis colon cancer (HNPCC), has also been associated with endometrial and ovarian cancer. Incidence rates are highest in industrialized countries other than Japan. Obesity: Some research indicates that women who were overweight have a higher rate of death from ovarian cancer in. The risk increased by 50 percent in the heaviest women.

What is Ovarian Cancer?

Ovarian cancer begins in a woman's ovaries. Women have two ovaries, one on each side of the pelvis. The ovaries produce eggs. They are also the main source of the female hormones estrogen and progesterone. Many types of tumors can start in the ovaries. Some are benign (non-cancerous) and never spread beyond the ovary. Women with these types of tumors can be successfully treated by removing one ovary or the part of the ovary that has the tumor. Other types of tumors are malignant (cancerous) and can spread to other parts of the body.

Types of Ovarian Cancer

Types of Ovarian Cancer As a rule, tumors in the ovary are named for the type of cell from which they were initiated and whether the tumor is benign or malignant. There are three main types of tumors: Germ cell tumors start from the cells that produce the eggs (ova). About one in 20 ovarian cancers are germ cell tumors. Germ cells are those that form the eggs. Most germ cell tumors are not cancer, although some can be. There are several sub-types of germ cell tumors. Most are benign but some are cancerous. Stromal tumors start from connective tissue cells that hold the ovary together and produce the female hormones. Stromal tumors can be either benign (non-cancerous) or cancerous. More than half are found in women over age 50. Epithelial tumors start from the cells that cover the outer surface of the ovary. Epithelial ovarian tumors can be further divided into three sub-groups: Benign epithelial tumors do not spread and usually do not lead to serious illness. Tumors of low malignant potential (LMP tumors) do not appear to be clearly cancerous. They are also known as borderline tumors. These tumors affect women at a younger age than other ovarian cancers. They grow slowly and are much less serious than most ovarian cancers. Epithelial ovarian cancers, which account for nearly nine out of 10 ovarian cancers. Cancer cells of this type of tumor have certain features that can be seen under a microscope and that allow doctors to further classify them. These kinds of tumors are also given a grade depending on how closely the cells look like normal cells. Grade 1 means the cells look more normal; grade 3 look less normal, and grade 2 is in between. Primary peritoneal carcinoma is a cancer much like epithelial ovarian cancer but it starts outside of the ovaries. It grows from the cells that line the pelvis or abdomen. These cells look like the cells along the surface of the ovaries. Women who have had their ovaries removed can still get this type of cancer. Symptoms of this cancer are much like those of ovarian cancer. Treatment is also similar. An ovarian cyst is fluid that collects inside an ovary. Many of these cysts are normal. The fluid will most often be absorbed and the cyst will go away in time without any treatment. But if the cyst is large or happens in childhood or after menopause, the doctor may suggest further tests or treatment.

Famous & Notable Women Whom Have Died From Ovarian Cancer

Alice Pearce, actress (died at age 48)
Anais Nin (author) Died 1/14/77
Angelina's Mom~Marcheline Bertrand, actress and mother of Angelina Jolie (died on January 27, 2007 at age 56)
Caitlin Clarke, actress (died at age 52)
Camille Monet – Model
Cassandra Harris, Australian actress/wife of Pierce Brosnan (died at age 43)
Clare Boylan, Irish writer (died at age 58)
Coretta Scott King, wife of civil rights activist Rev. Martin Luther King, Jr. (died 1/30/06 at age 78)
Diana Dors, actress, also known as Diana d'Ors (died at age 52)
Dixie Lee Crosby – singer and actress; Bing Crosby’s 1st wife; died at age 40
Dolly Haas, actress/singer; wife of Al Hirschfeld (died at age 84)
Elizabeth Tilberis, Harper's Bazaar Editor-in-Chief (died at age 51) Died 4/20/99. Born 10/27/47
Ella Grasso, former Connecticut governor, and the first woman ever to be elected governor in her own right
Evelyn Ankers, actress (died at age 67)
Gay Delanghe, modern-dance choreographer and performer
Gilda Radner, actress/comedienne/Saturday Night Live alumna (died at age 42) Died 5/20/89.
Helen Cresswell, British writer and author (died at age 71)
Jackie Walters, sister of Barbara Walters
Janet Sandell, South African social activist (died at age 70)
Jessica Tandy, actress; died at age 85; Died 9/11/94.
Jill Chaifetz, American lawyer and children’s right advocate (died at age 41)
Joan Hackett, actress (died at age 49) Died 10/8/83.
Laura Nyro, singer (died at age 49; her own mother, Gilda Nigro, also died of ovarian cancer
Laurie Beechman, actress/singer (died at age 43)
Linda Smith, comedienne, actress; head of the British Humanists' Association (died at age 48)
Loretta Young, Oscar-winning actress (died at age 87) Died 8/12/90.
Lynda Gibson (comedian)
Madeline Kahn, actress, singer and comedienne (died at age 57) Died 12/3/99. Born 9/29/42
Marcheline Bertrand, actress and mother of Angelina Jolie (died on January 27, 2007 at age 56)
Margot Fonteyn (1919 - 1991) was one of the greatest ballerinas
Mary I of England, Mary Tudor; British Queen Mary I (died either of uterine cancer or ovarian cancer age 42
Mildred Dean, mother of American actor James Dean; she died when Dean was 9 years old
Patsy Ramsey, mother of the late JonBenet Ramsey (died at age 49)
Robert Eads, American female to male transsexual who was refused medical treatment in the state of Georgia ( age 53)
Rosalind Franklin, British physical chemist and crystallographer (died at age 37)
Sandy Dennis, Oscar-winning actress (died at age 54) Died 3/2/92. Born 4/27/37
Shari Lewis, puppeteer / Lamb Chops; Died 8/2/98. Born 1/17/33
Susan Fleetwood, British actress (died at age 51)
The grandmother and great-grandmother of Eva Larue, star of the hit television series CSI Miami
· Dinah Shore, actress/singer (died at age 77)
· Helen Simpson Morosini, Mother of Dana Reeve, who was wife of Christopher Reeve (died at age 71)
· Katharine Clark Reilly (Actress)
· Mary Millar, British actress, most famous as "Rose" from Keeping Up Appearances (died at age 62)
· · Janet Margolin, actress (died at age 50)

Ovarian Cancer ~ Ovarian Cancer News

Wednesday, March 5, 2008

Ovarian cancers overexpress the antimicrobial protein hCAP-18 and its derivative LL-37 increases ovarian cancer cell proliferation and invasion

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